Negative effects of inbreeding can be triggered already during gene regulation, but if and how inbreeding influences gene expression is unknown in most organisms, including in birds. To evaluate whether inbreeding affects gene expression over the genome, we performed an expression study of inbred and outbred zebra finch chicks. We used a microarray approach and analysed more than 10,000 genes. However, inbreeding did not affect gene expression much; only one gene was upregulated in inbred individuals, and then only in females. The weak effect of inbreeding on gene expression in zebra finches contrasts the situation in e.g. fruitflies.
Please find the paper in Biology Letters:
Hansson B, Naurin S, Hasselquist D (2014) Does inbreeding affect gene expression in birds? Biol. Lett., 10, 20140648.